iTunes 12.5.1.21will not open

For general advice see Troubleshooting issues with iTunes for Windows updates.

The steps in the second box are a guide to removing everything related to iTunes and then rebuilding it which is often a good starting point unless the symptoms indicate a more specific approach. Run the installer as the administrator.

Review the other boxes and the list of support documents further down the page in case one of them applies.

The further information area has direct links to the current and recent builds in case you have problems downloading, or want to revert to an older version if the current one won't work properly for you at the moment.

Your library and device backups should be unaffected by these steps but there are links to backup and recovery advice should it be needed.

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Delete the iTunes shortcuts from the start menu, desktop, task bar, or similar, then repair iTunes from the programs and features control panel.

Otherwise try Fix unexpected quits or launch issues in iTunes for Windows - Apple Support or Troubleshooting issues with iTunes for Windows updates.

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I have tried all and still nothing