I can't click anything in the bottom right corner of my screen?

Hi,

There was no drop or software update or anything installed prior to this failing to work. It looks like in the bottom right corner of my screen (about a 3cm^2 area) doesn't work? If I'm in my web browser and I'm trying to click something in the bottom right corner, it acts as if I clicked a different, invisible app (turns the chrome window grey as if I clicked off of it and nothing happens). Mousing over an object there it recognizes that it can be clicked on (the little hand shows up or the capital I for a box to type in), but it does not work. I'm on a Macbook Pro 13" mid 2012 running Yosemite 10.10.4. It's quite annoying, has anyone had a similar problem? I've restarted the computer and it wasn't following any updates to any apps or anything of the sort.