iTunes could not connect to iPhone because an invalid response was received from the device.
iTunes 12.2.1.16
I've never had this problem before.
iPhone 5c, Windows 8
iTunes 12.2.1.16
I've never had this problem before.
iPhone 5c, Windows 8
Get the latest version of iTunes - Apple Support
Check your USB connections
If you see error 4005, 4013, or 4014, learn what to do. If you see one of the errors below, you might have a USB connection issue:
- 13, 14, 1600, 1601, 1602, 1603, 1604, 1611, 1643-1650
- 2000, 2001, 2002, 2005, 2006, 2009
- An error message that includes, "invalid response"
Use these steps to see if the issue is with your USB cable, USB port, or computer. Try again after each step:
- Use the USB cable that came with your device. If you don't have it, try a different Apple USB cable.
- Switch to a different USB port on your computer. Don't plug into your keyboard.
- Plug into a different computer.
- If you still see the error, you can check for other USB issues, issues with third-party security software, and issues with hardware.
If the issue continues, contact Apple Support.
What version of iOS are you using on your iPhone 5c? You need iTunes 12.5.1.21 for iOS 10.
iTunes could not connect to iPhone because an invalid response was received from the device.