turn off pop-up blocker for a specific software program on MacBook Pro running El Capitan

No, but Google Chrome has a similar switch. However, you wanted to turn ad blocking off on a site-selective basis. Chrome cannot do that either. But with Google browsers, you do that by adding an extension. Just like in Safari. I don't think Eric read this entire thread, hence, he gave the same stock answer I originally gave.

Google Chrome is a Web browser , not a search engine. Modern Web browsers such as Chrome, Microsoft Edge, Firefox , etc have search plugins built-in that will have a default search engine ( such as Google , Bing, or Yahoo ) selected, but you can always change it from the default to the search engine of choice.

With that cleared up, I gather that your Web browser that your question about is Google Chrome. and that your OS is Mac OS X . Assuming that is all true, Click on Chrome->Preferences and type "popup" in the settings search window. There you'll be able to add sites to the whitelist to allow browser popup windows.

The built-in blocker cannot be used in that way. However, there are ad blockers that install as Safari extensions that can be selectively disabled for a site. I use one called AdBlock Ultimate.

Safari/Preferences/Security and uncheck Block pop-up windows.