iTunes 12.7 won't open!

i had this problem as well -spent about a week trying to find a solution. if you download iTunes again (without removing the prior iTunes or messing with any locations to save it in your hard drive) it fixes the issue without erasing your prior settings. it just seemed to "re-vamp" the update to make it work. hope this helps. i also have a mac. it opened immediately after the install was done.

You can try reinstalling the current version of iTunes from https://www.apple.com/itunes/download/ over the top of the existing one. Or see this guide to uninstall iTunes from a Mac: http://www.inforaid.com/how-to-uninstall-itunes-from-mac-os-x-best-method/ then restore one of these recent builds direct from Apple's secure servers:

See also Empty/corrupt iTunes library after upgrade/crash for steps to roll back to the pre upgrade version of your iTunes database if required. Note iTunes 12.7 may have rearranged any iTunes U content into Podcasts or other sections of the library.

tt2

Other than the teardown guide I linked to earlier I don't really have anything further to suggest on the removal front, however this post includes links to the more recent builds: Re: iTunes wont open..

tt2

I have the same issue. I uninstalled and reinstalled iTunes several times. It didn't work, then suddenly it did for one day. Now, again today, it won't open. I am running El Capitan on a 2012 iMac. Any help would be greatly appreciated. Please note, I am not a computer geek in anyway. I can follow directions though, so if you have an idea, please be detailed. Thanks!

You're welcome. 🙂

tt2