MacBook Pro slowing down; system preferences won't open; safari toolbar incomplete

Recently I downloaded two new applications to my MacBook Pro (Adobe Pro and Big Fish Games). My computer slowed way down and I decided that I didn't want those applications. I have tried to uninstall, but worry I didn't do it completely, as I am having trouble with incredibly slow booting up time, slow internet response, a very annoying creative cloud icon on my safari toolbar. Now my safari toolbar is messed up - no icons, no arrows (just blank spaces). I have tried to remove applications to trash can, removed utilities associated with Adobe, and rebooted. I need some help as to what else I can do. And system preferences crashes every time I try to open it.