du and ls show different file sizes

I am using a MacAir with High Sierra and I noticed something odd in one of VirtualBox Directories. I can use ls -l to look at file sizes and I get

Odin-2:server_io_1_1510416322051_80277 rsplinter$ ls -l

total 3689032

drwx------ 6 rsplinter staff 192 Nov 12 08:29 Logs

-rw------- 1 rsplinter staff 1846870016 Nov 12 08:48 box-disk001.vmdk

-rw------- 1 rsplinter staff 1932360271360 Nov 12 08:48 box-disk002.vmdk

-rw------- 1 rsplinter staff 2686976 Nov 12 08:48 box-disk003.vmdk

-rw------- 1 rsplinter staff 2686976 Nov 12 08:48 box-disk004.vmdk

-rw------- 1 rsplinter staff 2195266973696 Nov 12 08:48 box-disk005.vmdk

-rw------- 1 rsplinter staff 2621440 Nov 12 08:48 box-disk006.vmdk

-rw------- 1 rsplinter staff 2621440 Nov 12 08:48 box-disk007.vmdk

-rw------- 1 rsplinter staff 2621440 Nov 12 08:48 box-disk008.vmdk

-rw------- 1 rsplinter staff 1728720041984 Nov 12 08:48 box-disk009.vmdk

-rw------- 1 rsplinter staff 2621440 Nov 12 08:48 box-disk010.vmdk

-rw------- 1 rsplinter staff 2621440 Nov 12 08:48 box-disk011.vmdk

-rw------- 1 rsplinter staff 7790 Nov 12 08:48 gluster_gluster0_1510416337924_10125.vbox

-rw------- 1 rsplinter staff 7790 Nov 12 08:29 gluster_gluster0_1510416337924_10125.vbox-prev

But if I use du -skH I get

Odin-2:server_io_1_1510416322051_80277 rsplinter$ du -skH *

576 Logs

1802804 box-disk001.vmdk

19132 box-disk002.vmdk

2472 box-disk003.vmdk

2472 box-disk004.vmdk

2784 box-disk005.vmdk

2408 box-disk006.vmdk

2408 box-disk007.vmdk

2408 box-disk008.vmdk

2796 box-disk009.vmdk

2408 box-disk010.vmdk

2408 box-disk011.vmdk

8 gluster_gluster0_1510416337924_10125.vbox

8 gluster_gluster0_1510416337924_10125.vbox-prev

Does anyone know why I see some files with massively different sizes? This system only has a 500GB SSD so TB size files is out of the question and they cannot be correct from "ls -l", but there they are. This is also affecting my ability to do Time Machine backups as well.