Unfortunately, no luck. I first tried installing the Combo Update under the normal non-safe mode. It too produced the same "unable to install" result. I then tried to boot into Safe Mode but the system would not boot - after prompting me for my signon, the progress bar moved very slowly until the end of it's window and then sat there. I let it alone for an hour, then powered off, rebooted normally, tried the roboot to Safe Mode and got the same result. I ran Disk Utility, First Aid, which ran without errors, tried it again and got the same hang trying to go to Safe Mode. There was a Guest User account setup on my system (Apple set this up from a previous service call) but when I use it, all it gives me is Safari. When I exit Safari, it reboots back to my normal ID (although it doesn't prompt me to signon to my normal ID, which I thought was strange). I have a MacBook Pro 17" mid 2010, if that's any help diagnosing the issue.