I have the same issue on my iMac (21.5-inch, Late 2015) since I installed High Sierra shortly after release.
Not only PDF I do create, but all PDF content I have.
Now it's High Sierra version 10.13.2 (17C88) and the problem is still there. It seems to be a very well known problem as it was reported many times, in different languages, to Apple.
It's indeed very annoying to me; I couldn't find any fix. Only solution seems to forget about Preview (!!) and switch to Google Chrome for instance. But it's not a solution to me.
Also, after the update to High Sierra, I lost all the comments I had included in a PDF document (important 60pp work document ...) with Preview with the previous 10.12 version (up to date) I had before. Only empty sticky notes in my document now. I guess other users have the same kind of problems.
==> Really no bug fix coming...?
It's not easy to switch to another software after decades (...) using Preview being quite satisfied with it.
Thanks if anyone has information about this.