The Application "YADA YADA YADA" Is not Open Anymore

What's up Group!

So our company did a mass upgrade in-place from Yosemite (10.10.5) to Sierra (10.12.6) and ever since, we've been plagued with this dang blasted error:

And it's not just Photoshop. We've seen it with Preview. We've see it with Outlook. We've seen it with 3rd party apps. We have tried everything under the hat. Nothing works. This problem still persists even after all the little tips and tricks folks have suggested to fix this. Has anyone or does anyone know whats causing this? It's becoming a real problem for us. Please advise.