No refund is guaranteed. Realize Apple's terms of purchase in the USA are, "All Transactions are final" (https://www.apple.com/legal/internet-services/itunes/us/terms.html), but some countries have different laws so check terms for your country at: http://www.apple.com/legal/internet-services/itunes/. If sales are final then it is Apple's decision if they want to grant a refund. You can always ask, and people do get refunds on a case by case basis, but Apple can also say no.
Get help with an item purchased from the App Store, iTunes Store, or iBooks Store - https://support.apple.com/HT204084
Other ways to contact iTunes Support: