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Question: iMac running very slow

My iMac has been running terribly slow - I have investigated various aspects to check - eg CPU/memory usage - and finally have run a EtreCheck report see below. Can I have suggestions please to improve this?



EtreCheck version: 4.3.1 (4D024)

Report generated: 2018-05-27 10:05:04

Download EtreCheck from https://etrecheck.com

Runtime: 32:32

Performance: Poor

Problem: Computer is too slow

Major Issues:

Anything that appears on this list needs immediate attention.

No Time Machine backup - Time Machine backup not found.

Poor performance - EtreCheck report took over 10 minutes to run. This is very unusual.

Minor Issues:

These issues do not need immediate attention but they may indicate future problems.

Clean up - There are orphan files that could be removed.

Unsigned files - There is unsigned software installed. They appear to be legitimate but should be reviewed.

32-bit Apps - This machine has 32-bits apps that may have problems in the future.

Hardware Information:

iMac (Retina 5K, 27-inch, Late 2015)

iMac Model: iMac17,1

1 3.2 GHz Intel Core i5 (i5-6500) CPU: 4-core

8 GB RAM - Upgradeable

BANK 0/DIMM0 - 4 GB DDR3 1867 ok

BANK 0/DIMM1 - Empty

BANK 1/DIMM0 - 4 GB DDR3 1867 ok

BANK 1/DIMM1 - Empty

Video Information:

AMD Radeon R9 M380 - VRAM: 2048 MB

iMac

Drives:

disk0 - APPLE HDD ST1000DM003 1.00 TB (Mechanical)

Internal SATA 3 Gigabit Serial ATA

disk0s1 - EFI (MS-DOS FAT32) [EFI] 210 MB

disk0s2 [Core Storage Container] 999.35 GB

disk1 - Macintosh HD (Journaled HFS+) 998.98 GB

disk0s3 - Recovery HD (Journaled HFS+) [Recovery] 650 MB

Mounted Volumes:

disk1 - Macintosh HD 998.98 GB (670.26 GB free)

Journaled HFS+

Mount point: /

Network:

Interface en0: Ethernet

Interface en6: iPad

Interface en1: Wi-Fi

802.11 a/b/g/n/ac

One IPv4 address

Interface en5: iPhone

Interface en4: Bluetooth PAN

Interface bridge0: Thunderbolt Bridge

System Software:

macOS High Sierra 10.13.4 (17E202)

Time since boot: About 8 days

System Load: 1.98 (1 min ago) 1.67 (5 min ago) 1.61 (15 min ago)

Security:


SystemStatus
GatekeeperMac App Store and identified developers
System Integrity ProtectionEnabled

Unsigned Files:

Launchd: ~/Library/LaunchAgents/com.skype.skype.shareagent.plist

Executable: /Applications/Skype.app/Contents/Library/LaunchServices/com.skype.skype.shareag ent.bundle/Contents/MacOS/com.skype.skype.shareagent

Details: Exact match found in the whitelist - probably OK

Launchd: /Library/LaunchDaemons/com.microsoft.office.licensing.helper.plist

Executable: /Library/PrivilegedHelperTools/com.microsoft.office.licensing.helper

Details: Exact match found in the whitelist - probably OK

Launchd: /Library/LaunchAgents/com.brother.LOGINserver.plist

Executable: /Library/Printers/Brother/Utilities/Server/LOGINserver.app/Contents/MacOS/LOGIN server

Details: Exact match found in the whitelist - probably OK

32-bit Applications:

29 32-bit apps

Kernel Extensions:

/Library/Extensions

[Not Loaded] Dropbox.kext (Dropbox, Inc., 1.8.8 - SDK 10.11)

[Not Loaded] MB_MBAM_Protection.kext (Malwarebytes Corporation, 3.3 - SDK 10.13)

System Launch Agents:


[Not Loaded]8 Apple tasks
[Loaded]162 Apple tasks
[Running]121 Apple tasks
[Other]2 Apple tasks

System Launch Daemons:


[Not Loaded]37 Apple tasks
[Loaded]167 Apple tasks
[Running]129 Apple tasks
[Other]2 Apple tasks

Launch Agents:


[Loaded]com.microsoft.update.agent.plist (Microsoft Corporation - installed 2018-04-11)
[Other]com.adobe.ARMDCHelper.cc24aef4a1b90ed56a725c38014c95072f92651fb65e1bf9c8e43c37a2 3d420d.plist (Adobe Systems, Inc. - installed 2018-02-17)
[Running]com.malwarebytes.mbam.frontend.agent.plist (Malwarebytes Corporation - installed 2018-05-23)
[Running]com.brother.LOGINserver.plist (? a1772de2 - installed 2016-03-11)

Launch Daemons:


[Running]com.adobe.ARMDC.SMJobBlessHelper.plist (Adobe Systems, Inc. - installed 2018-02-17)
[Running]com.malwarebytes.mbam.settings.daemon.plist (Malwarebytes Corporation - installed 2018-05-23)
[Loaded]com.microsoft.autoupdate.helper.plist (Microsoft Corporation - installed 2018-04-11)
[Other]com.malwarebytes.mbam.rtprotection.daemon.plist (Malwarebytes Corporation - installed 2018-05-23)
[Loaded]com.adobe.fpsaud.plist (Adobe Systems, Inc. - installed 2018-04-29)
[Loaded]com.microsoft.office.licensing.helper.plist (? 6d8cb30e - installed 2010-08-25)
[Running]com.adobe.ARMDC.Communicator.plist (Adobe Systems, Inc. - installed 2018-02-17)
[Loaded]com.microsoft.office.licensingV2.helper.plist (Microsoft Corporation - installed 2017-06-10)

User Launch Agents:


[Running]com.spotify.webhelper.plist (Spotify - installed 2018-01-17)
[Loaded]com.google.keystone.agent.plist (Google, Inc. - installed 2018-02-04)
[Running]com.dropbox.DropboxMacUpdate.agent.plist (Dropbox, Inc. - installed 2018-04-21)
[Other]com.valvesoftware.steamclean.plist (? 0 - installed 2017-11-10)
[Loaded]com.skype.skype.shareagent.plist (? 0 - installed 2017-11-17)

Internet Plug-ins:

AdobePDFViewerNPAPI: 17.012.20098 (installed 2018-05-19)

FlashPlayer-10.6: 29.0.0.171 (installed 2018-05-10)

QuickTime Plugin: 7.7.3 (installed 2018-04-08)

AdobePDFViewer: 18.011.20040 (installed 2018-05-19)

Flash Player: 29.0.0.171 (installed 2018-05-10)

SharePointBrowserPlugin: 14.7.7 (installed 2017-09-15)

User Internet Plug-ins:

ZoomUsPlugIn: 4.0.22115.0123 (installed 2017-01-25)

3rd Party Preference Panes:

Flash Player (installed 2018-04-29)

Time Machine:

Time Machine Not Configured!

Top Processes by CPU:


Process (count)Source% of CPULocation
WindowServerApple11
InstallerApple7
kernel_taskApple4
kextdApple1
Google Chrome Helper (10)Google, Inc.1

Top Processes by Memory:


Process (count)SourceRAM usageLocation
Google Chrome Helper (11)Google, Inc.1.45 GB
kernel_taskApple955 MB
mdworker (22)Apple579 MB
Evernote?266 MB/Applications/Evernote.app
Dropbox (3)?239 MB/Applications/Dropbox.app

Top Processes by Network Use:


ProcessSourceInputOutputLocation
Dropbox?12 MB1 MB/Applications/Dropbox.app
mDNSResponderApple5 MB2 MB
netbiosdApple161 KB27 KB
apsdApple5 KB4 KB
RTProtectionDaemonMalwarebytes Corporation3 KB1 KB

Top Processes by Energy Use:


Process (count)SourceEnergy (0-100)Location
WindowServerApple1
DockApple1
Google Chrome Helper (11)Google, Inc.1
Google ChromeGoogle, Inc.1
installdApple0

Virtual Memory Information:


Available RAM2.39 GB
Free RAM236 MB
Used RAM5.61 GB
Cached files2.16 GB
Swap Used47 MB

Software Installs (past 30 days):


NameVersionInstall Date
Numbers5.02018-05-05
Pages7.02018-05-05
Keynote8.02018-05-05
Security Update 2018-0012018-05-05
Adobe Flash Player29.0.0.1712018-05-10
Evernote7.1.12018-05-13
Adobe Acrobat Reader DC (18.011.20040)18.011.200402018-05-19
Microsoft PowerPoint for Mac16.13.180523042018-05-26
Microsoft Excel for Mac16.13.180523042018-05-26
Microsoft OneNote for Mac16.13.180523042018-05-26
Microsoft Word for Mac16.13.180523042018-05-26
Microsoft Outlook for Mac16.13.180523042018-05-26

Clean up:

~/Library/LaunchAgents/com.valvesoftware.steamclean.plist

/Users/***/Library/Application Support/Steam/SteamApps/steamclean

Executable not found

Diagnostics Information (past 7 days):

2018-05-26 11:31:35 Skype.app CPU (2 times)

/Applications/Skype.app

End of report

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Question: iMac running very slow