New MacPro, Logic Pro, RAID and streaming files for a sampler.

I’m setting up a MacPro to use with Logic Pro and Ableton Live. The primary use for this computer is music creation above all else. After reading recommendations on this forum I ordered the basic 4x2.66 and pulled the included memory and hard drive, replacing them with 4x1Gig memory chips and 4x500Gig WD5000YS hard drives. After spending 8 hours installing the OS, Logic Pro and some other software I realized that I forgot to consider RAID. Because the my main concern is streaming samples and loops along with writing output I think I will be fine leaving one 500Gig HD as the boot drive and setting up the other three drives in Raid 0. I do have a question on this setup.

Should I accept the default setups when I create the RAID or should I tweak block size to handle special needs for music creation? While some of the audio files on output will be quite large, the nature of a streaming sampler is to read the beginning of every sample file. Example, while a piano has 88 keys a good sample set for that piano will multiple samples at different velocities for each key. The software will load the beginning of every sample into memory, and when a note is played it will start playing the note in memory and immediately load the rest of the samples for that note into memory. We are talking a lot of files open and a lot of quick reads to avoid glitches.

Any suggestions on how to best set up my RAID for lots of multiple files to be read rather than dealing with very large individual files?

Thanks