Yeah, I second chaining different Plug-Ins. Also try using Bus Sends and Aux tracks to blend certain amounts of effects. With this, try mixing 3 or more Guitar Amps on Aux Tracks with different settings on each, or slightly different from each one, and pan them to something you like. I have found this to be extremely awesome. I got the idea after reading how they engineered 10,000 Days by Tool and found Adam Jones uses 3 cabinets with an SM57, 421, and another mic to complement the 57 and 421, and they put 3 mics on the cabinets, so the guitar sound was made of 9 tracks and were never EQ'ed because they could use those tracks as EQ and tweak it the way they wanted.
http://mixonline.com/recording/projects/audiomaking_toolsdays/
There's the article. Good luck and enjoy!
~trevor