PJ,
Your wife has it exactly right. The prints are not quite as nice as I could get them with my pro profiles and I have, effectively, lost my WYSIWYG system. Like your wife, I am also a pro photographer and find this loss of control very frustrating. Too difficult to call whether the problem is Adobe's or Epson's. One thing is absolutely certain, they will each point the finger at the other. Adobe say that CS3 is fine with Leopard, but that some functionality is lost in CS2, so CS3 should be OK.
I am going to try trashing my photoshop preferences today as suggested by Mike and see what happens. I will report back after doing so. I also have an Epson Pro 4800 Mike, but I haven't even tried to sort this out yet. It was always temperamental! I hate to think what that exercise is going to be like!
Interestingly, my Epson 950 is now working again, using the technique I mentioned above. It hasn't worked since I went Mac three years ago! It refused to print anything. I had to clean the heads several times to clear out three years of dried ink, but it works fine!
Regards,
David