I was experiencing problems with the Apogee Duet and my MacBook Pro recently and was unable to find any posts directly related to the issues I was having. It ended up being a Firewire issue and I hope to save anyone some time with what I learned from my snafu.
Basically, my MBP would recognize the Duet only sometimes and when it did, it wouldn't transmit sound properly- intermittent and unresponsive. Troubles would exponentially grow as I fumbled with settings in Logic, Apogee Maestro (tried multiple versions), and my sound preferences which would actually completely hang the computer giving me the spinning beach ball of death. After exchanging Duets and swapping Firewire cables, and even a clean install of Leopard, I was frustrated to say the least.
I had an e-mail support ticket with Apogee bouncing back and forth, but decided to just call their tech guys and go through the motions in real time. After I tried a number of things he suggested with no success, I had him stumped as well. We were both suspecting a Firewire connection issue despite the fact that the Duet was always receiving power (indicated by the green LED lights). It was near the end of the call that he suggested one last ditch effort:
*Power the MacBook Pro off, disconnect the power cable, disconnect the MacBook Pro battery, and wait 15 minutes. Then, re-attach battery and cable and turn it on.*
He told me he had heard that this "resets" the firewire ports. Well, it sounded desperate but I decided it was worth a try before going to the service department at my local authorized Apple dealer. Somehow this worked! I've tried repeating different things on my computer that had caused the problems I had been experiencing, and everything worked perfectly. I hope that if anyone experiences the same strange problem, that this helps them before they completely lose it! Otherwise, I would suggest calling Apogee Tech support as I found them very polite and helpful.
*Apogee Technical support: 1-310-584-9394*