Ok maybe this will help: You get free support from Apple for 90 days on your software purchase.
http://www.apple.com/support/
Bottom left of page you can call them. It works!
After updating to 10.6.1 I still had the problem. So called them (from Vietnam).
1. They had me look at the mail accounts. For some reason (SN upgrade?) had disconnected my.me account from being registered.
2. They had me create a new network connection profile called something other than automatic. And switch to the new profile. I erased automatic and left the new one.
(system preferences, networks, +, add new name)
More than 2 hours later my mail and browsers still work.
Having problems? Call Apple. It is free and included in your software upgrade for 90 days.