Mojave Keychain questions: Red Xs, LastPass/Keychain conflicts

I'm exploring Keychain.

In "login", there are several listed.

Many have a red x on them. I understand, in general, these can be deleted safely as they will be recreated when go to those sites again.

Does this also apply to those that appear to be for Apple? , for example:

com.apple.ubiquity. ....

com.apple.idms.appleid ....

Apple Application Integration ....

Does this also apply to other sections of Keychain (Local Items, System, System Roots) where I see red Xs? I like things neat and tidy and really want to clean this up a bit ... many of the red x items are old. How safe am I going through and just deleting many of them? If someone can help me understand, that would be helpful.

Does anyone know whether Keychain is as secure for password keeping as, say LastPass or 1Password? I have LastPass ... and what got me started on all of this is that there seems to be some conflict between the two, especially in Safari. Any light someone can shed on this would also be great.

Thanks.

Kathy