MacBook Freezes and every apps becomes unresponsive

Unfortunately, I could not access the PDF file. It says "gone." As I stated before, you need to be sure you have no 32-bit processes trying to run. From the first EtreCheck report it seems you are running out of memory which forces the system to swap out memory to the disk. This is not only slower than RAM but also can become corrupted, thus causing crashes.

Meanwhile, you should look through the report as well as the Console app for information that may lead you to what is causing the problem. Also, see the following:

A Troubleshooting Procedure that may Fix Problems with macOS El Capitan or Later

You should try each, one at a time, then test to see if the problem is fixed before going on to the next.

    Be sure to backup your files before proceeding if possible.

1. Shutdown the computer, wait 30 seconds, restart the computer.
2. Disconnect all third-party peripherals.
3. Resetting your Mac's PRAM and NVRAM
4. Reset the System Management Controller (SMC)
5. Reset your Startup Disk and Sound preferences, if needed, after resetting the PRAM.
6. Test in safe mode to see if the problem persists, then restart normally.  Use safe mode to isolate issues with your Mac and Playing Safe - what does Safe mode do?
7. Repair the disk by booting from the Recovery HD. Immediately after the chime hold down the Command and R keys until the Utility Menu appears. Choose Disk Utility and click on the Continue button. Select the indented (usually, Macintosh HD) volume entry from the side list.  Click on the First Aid button in the toolbar. Wait for the Done button to appear. Quit Disk Utility and return to the Utility Menu. Restart the computer from the Apple Menu.
8. Repair permissions on the Home folder: Resolve issues caused by changing the permissions of items in your home folder.
9. Create a New User Account Open Users & Groups preferences. Click on the lock icon and enter your Admin password when prompted. On the left under Current User click on the Add [+] button under Login Options. Setup a new Admin user account. Upon completion log out of your current account then log into the new account. If your problems cease, then consider switching to the new account and transferring your files to it - Transferring files from one User Account to another.
10. Reinstall OS X by booting from the Recovery HD using the Command and R keys. When the Utility Menu appears select Install OS X then click on the Continue button.
11. Erase and Install OS X Restart the computer. Immediately after the chime hold down the Command and R keys until the Apple logo appears. When the Utility Menu appears:

     1. Select Disk Utility from the Utility Menu and click on the Continue button.

     2. When Disk Utility loads select the drive (out-dented entry) from the Device list.

     3. Click on the Erase button in Disk Utility's toolbar. A panel will drop down.

     4. Set the Format type to APFS (for SSDs only) or Mac OS Extended (Journaled.)

     5. Click on the Apply button, then wait for the Done button to activate and click on it.

     6. Quit Disk Utility and return to the Utility Menu.

     7. Select Install OS X and click on the Continue button.

This is not Apple Support. I do not have access to the 100 or so helpers that may stumble onto your posted problem.

FYI: These are user-only forums. You are not speaking to Apple. if you need to speak with Apple Support, then contact product and tech support:  Contacting Apple for support and service including international calling numbers.

Thank you for your understanding and support.

You have one 32-bit app still installed - may be Flash and/or something else. You cannot run 32-bit apps in Catalina.

You haven't sufficient RAM - only 4GBs installed. To run all the apps you have running contiguously requires more RAM. If you cannot upgrade the RAM, then reduce the workload to one or two apps.

I assume you did not bother to read or check the output of your EtreCheck report. It has so many unprintable characters as to make it difficult to read.

EtreCheck produces a text report that you can select, copy, and paste directly into the message editor here. Or it can be pasted into an Additional Text block by clicking on the icon just left of the image entry icon in the bottom toolbar.

I don't see anything in the Etrecheck report that would indicate a problem other than what I've posted earlier.

Check that Skype and Chrome are current, although I would suggest trying to use Safari rather than Chrome. Only use Skype when connecting with Windows users, otherwise use FaceTime. Both of those apps are known to cause problems for macOS.

Read through the Etrecheck report. It's pretty understandable when pointing out possible areas of concern. However, it's a moment in time snapshot. It can't catch an adverse event unless you run it as the bad event occurs. I don't think that's possible.

It seems you have insufficient RAM for all the software you run concurrently. This results in running out of memory forcing the OS to use disk space in lieu of RAM. This can cause slowdowns and other glitches that may cause the computer to be unresponsive or to crash. You cannot add RAM to the computer, so you need to reduce the number of concurrent apps/add-ons running in order to stop the system having to page memory to the disk. It's also possible that the temporary use of disk space causes a severe shortage of disk space leading to crashes.

If you are unable to devote the time for tracing all of this, then the next best thing would be to take it in to the Apple retailer for help. But you would then need another computer to use during the time it takes for repair.

When you run Etrecheck you get a report on the computer with lots of additional information that isn't included in the report such as indications about a problem and information about where the problem may be and how to fix it. I don't know what more to suggest.

Not at all. You thought this was Apple Support; it's an honest mistake. You did not hurt my feelings in the least. I wish that I could help you more but it seems that I haven't quite nailed your problem. I have provided you with what I know about kernel panics and found in your Etrecheck report. Unfortunately, nothing helped identify what is going on. I commented on the RAM situation because I noted what processes seemed to be running and that the OS was using VM swap on the disk which indicates the system was out of RAM and was paging memory out in larger than normal size. But you said you watched what you loaded to not overtax memory. At this point the only other thing I haven't seen is the full kernel panic log in case it may offer some additional clues.

In any event, since I cannot really be of much more help, have a Happy New Year. Perhaps another helper will see this question is still unsolved and provide better help.