Occasionally Sluggish Performance with Mac Pro (Late 2013)

Do you recognize the profiles?

To remove a configuration profile in macOS:

From the Apple menu, select System Preferences....

From the View menu in System Preferences, select Profiles.

Note:

Profiles won't be visible until you have at least one profile installed.

Select the profile you want to remove, and then press the - (minus) button. Click Remove to remove the profile.

CleanMyMac is still there, remove this file from Launch Daemons & restart...

com.macpaw.CleanMyMac3.Agent.plist

Why no backup?

No Time Machine backup - Time Machine backup not found.

And worst of all...

Failing RAM - RAM status failing.

DIMM1 - 16 GB DDR3 ECC 1866 ecc_errors

DIMM2 - 16 GB DDR3 ECC 1866 ecc_errors

EtreCheck is a simple little app to display the important details of your system configuration and allow you to copy that information to the Clipboard. It is meant to be used with Apple Support Communities to help people help you with your Mac.

http://www.etresoft.com/etrecheck

Pastebin is a good place to paste the whole report...

https://pastebin.com/

Or use the paperclip at the bottom of a Reply to attach the full report here. :)

Workable but harder for me to work with...the Note tool on the bottom of this editor's toolbar, as shown in the image, to copy and paste the output from EtreCheck.

Uninstall CleanMyMac per their directions & restart.

Top Processes Snapshot by CPU:

Process (count) CPU (Source - Location)

Adobe Premiere Pro 2020 550.81 %

Was Premiere active when test was run?

Single-bit errors are corrected in Hardware, on-the-fly, with only a stretched memory cycle. The data as corrected are perfect, and no errors are introduced into any other data. But the error persists in main store. The report should show that the modules are encountering (and correcting, as deigned) those correctable errors.

Only when an uncorrectable error occurs, such as most double-bit errors, does your Mac halt with a distinctive kernel panic, machine check, uncorrectable error or something similar, and multiple processors reporting the error. This is to prevent the error from poisoning your data by being propagated.

If all errors are correctable, there is no need to Halt. But there is reason to do some maintenance and eliminate the error-encountering modules so that full protection is restored.

start with Activity Monitor to see if this Is actually a CPU issue or something else:

See how apps affect Mac performance, battery runtime, temperature, and fan activity - Apple Support

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this article explains some of the nuances of running with ECC RAM memory:

User Tip: Mac Pro and Error Correcting Code RAM Memory

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Thanks Tom, I do believe failing RAM is the biggest problem.

Thanks Grant, great info, but why the report of bad RAM & no KPs?

Thanks for sharing your extensive knowledge Grant! :)