On my Mojave system, when I press Command-Tab, my cursor turns into a white gloved hand.
So I would suggest booting into Safe mode to see if it is 3rd party software
http://support.apple.com/kb/ht1564
This will not load any 3rd party additions, it will load some more conservative Apple drivers (may cause screen flicker), and it will clear some kernel caches (a cache is saved data in a form that can speed up a program, but is totally redundant to the original source, and thus can be safely cleared). Booting into Safe mode is just an experiment, but can frequently eliminate any 3rd party interference, or a cached item out-of-sync with the world. (Verify Safe mode via Applications -> Utilities -> System Information -> Software -> Boot Mode -> Safe vs Normal)
You should also try an SMC reset and an NVRAM reset
Reset the System Management Controller (SMC) on your Mac - Apple Support
https://support.apple.com/en-us/HT201295
How to reset NVRAM on your Mac - Apple Support
https://support.apple.com/en-us/HT204063