Virus? Safari keeps opening to "Any Search Manager" when I have it set to Google.

 You have adware/malware installed. Use  Malwarebytes Anti-Malware for Mac  https://www.malwarebytes.com/mac-download/. It may be necessary to run more than one scan. After scanning a couple of times, restart the computer and test. If necessary, follow the manual instructions.  Do not download any other programs that are listed in the articles.  

Search.anysearch.net uninstall.       https://malwaretips.com/blogs/remove-search-anysearch-net-macos/

Also check Safari/Preferences/General to see what is set as the Home Page.

Safari Homepage setting greyed out.       

About pop-up ads and windows in Safari – Apple Support

Remove the Any Search Manager extension by following the steps here:

How to install Safari extensions on your Mac - Apple Support

Good luck!