Bradford Bosley wrote:
I've had Avast, Private Internet Access VPN, and Malwarebytes installed for a long time with no issues. This only started after updating to 10.15.6. M̶y̶ ̶w̶i̶f̶e̶'̶s̶ ̶c̶o̶m̶p̶u̶t̶e̶r̶ ̶h̶a̶s̶ ̶n̶o̶t̶h̶i̶n̶g̶ ̶i̶n̶s̶t̶a̶l̶l̶e̶d̶ ̶a̶n̶d̶ ̶i̶t̶ ̶s̶t̶i̶l̶l̶ ̶h̶a̶s̶ ̶t̶h̶e̶ ̶s̶a̶m̶e̶ ̶i̶s̶s̶u̶e̶s̶.̶
I can appreciate that, however if you want to resolve your issue — I advise you to uninstall to get back to terra firma. Your SafeBoot mode test indicates you have third party software issue.
After that you can add them one at a time and test along the way.
With each point update also includes refined/improved security features as well; that may not bode well for your third party additions.
For added insight please reference:
Control access to your files and folders on Mac - Apple Support
Change Security & Privacy General preferences on Mac ...
macOS - Security - Apple https://www.apple.com/macos/security/
I can only see one Etrecheck report— I can not comment on your"wife's computer."