What’s running here? Lion 10.7 (10.7.5) as was mentioned (and as is seemingly confirmed by the Darwin kernel version 11.4.2), or maybe the final version for this Mac Pro (early 2008) OS X 10.11, or macOS 10.13 High Sierra per the community this is posted in? I’m going to here assume the the High Sierra posting location is incorrect, and that this is running OS X 10.7.5.
If you’re really running 10.7, get a backup, and try an upgrade to the final version for that Mac Pro; to OS X 10.11.
As mentioned above, kexts are a potential trigger. There’s one visible in the backtrace info.
The memory shown in the backtrace also doesn’t match what I see in the Mac Pro early 2008 specs; DDR2 667 MHz PC2-5333, when the specs indicate DDR2 800 MHz PC2-6400. Mismatched memory can cause issues.
There’s a collection of other hardware modifications visible here (storage and graphics don’t seem to match the specs, of what I’ve looked at), which pretty much means you’re going to have to start swapping parts and see what might be triggering this, if it’s not software. I’d start with swapping in 800 MHz memory, if it’s not software.
If you don’t already have a complete and current backup, get that first.