can apple pen be used in iPad mini 2?

Hey sandara128,

That's a great question! The 1st generation Apple Pencil can be used with a 5th generation iPad mini. Take a look at the following resource for all devices that will work with the Apple Pencil: Apple Pencil compatibility

Thanks for using Apple Support Communities.

Have a great day!

No. The second generation iPad mini (a.k.a., iPad mini2 - mini Retina) does not support Apple Pencil - as it (any many other older models of iPad) lack the necessary screen hardware with which the Apple Pencil interacts.

Here is a link the the full compatibility list for Apple Pencil:

Apple Pencil compatibility - Apple Support