Can I run Adobe CS6 on Catalina 10.15.7

See the information in the following: https://helpx.adobe.com/x-productkb/global/fix-macos-64-bit-compatibility-errors.html

including this excerpt:

Apps that don't work in Catalina

Most older Adobe apps were created using 32-bit architecture and do not work in Catalina. We have no plans to update apps that we no longer support or develop. The following table lists some common 32-bit Adobe apps that are not compatible with Catalina. (It is not a comprehensive list of all older 32-bit Adobe apps.)

Adobe ProductStatus and alternatives

...

Creative Suite appsNo updates planned. We recommend that you upgrade to Creative Cloud.Fuse

No. While it is 64 bit software, it also has a fair number of 32 bit dependencies. Mojave is the last version of macOS CS6 will run on without virtualization.