how to clean my Mac from malware

It depends on type of the Malware installed.

  How to remove  Any Search manager,  AristoleLookup, lkysearchds4649-a.akamaihd.net, 

  Landslidesearch, SafeFinder, Search Pulse, General net search,

  SearchMine,  SearchMaster,  Search Barron, Search Marquis,  SOCKS, UpgradeSearchSystem,  We know, ChillTab,  etc?

  Enter Discovery is a browser hijacker adware.

  Note: Malwarebytes for Mac will remove malware installed on your Mac..

           But these malware being very invasive, will change user settings.

           A user has to reset those settings.

Go step by step and test.

   1. Remove unknown profiles if present.

      System Preferences > Profiles

      Open System Preferences,  select “General and click  the “Profiles” icon ( a checkmark on a gear) .

      When Profiles pane opens, select the unknown profile and click the minus button at the bottom.

      Section: Remove a configuration profile from your Mac

      Profiles: https://support.apple.com/guide/mac-help/configuration-profiles-standardize-settings-mh35561/mac

  2. Remove unknown extensions:  Safari > Preferences > Extensions

      https://support.apple.com/guide/safari/use-safari-extensions-sfri32508/mac

   3. Check for adware.

       Run the latest release of Malwarebytes for Mac to remove malware/adware, if installed on your Mac.

       For instructions: Install Malwarebytes for Mac v4      Uninstall Malwarebytes for Ma

       Click the “FREE DOWNLOAD” button.

       Click the “Scan” button. Once done, quit Malwarebytes for Mac.

       Restart the computer and relaunch Safari holding the shift key down.

       Scan for Malware again.

       Additional steps  if necessary.

  4. Reset search engine:    https://support.apple.com/guide/safari/customize-your-search-ibrwe75c2a3c/mac

  5. Reset  Homepage.   https://support.apple.com/guide/safari/set-your-homepage-ibrw1020/mac 

  6. Check proxies. SOCKS?

      System Preferences > Network > Advanced > Proxies

      Deselect   any  proxies if selected.   

   7. Restart the Mac. Relaunch Safari holding the Shift key down. 

In some cases, after being changed by adware or malware, Safari's home page can become stuck. You will be able to edit the Homepage field in Safari's preferences, but the change will not stick. This appears to be a bug, and there is an odd workaround. Try this:

If Safari's home page is stuck

Credit: thomas_r

https://forums.malwarebytes.com/topic/236261-how-to-remove-weknow-malware-and-others/