Practically speaking, do I need to run an anti-virus software on my MacBook Air with M1 chip?

There are no known Viruses in the wild that self replicate and affect macOS. There are Malware and Adware that does affect macOS and are often times downloaded as part of an Application from Third Party UnTrusted Site and get installed along with the Application.

Are there any AntiVirus, Disk Cleaner, Optimizers, Un-installers, etc installed which should be removed as per Developers Instructions. They are useless, unneeded, cause havoc and interfere with the normal operation of the OS and may even Corrupt the OS requiring a Reinstallation. The Built-in Security of Big Sur is all that is required.

You do not need. If you want to check from malware you can use Malwarebytes app.