It says my memory application is full on my mini mac

Welcome to the Apple Support Communities.

I believe we need to proceed with an EtreCheck report. EtreCheck is a useful App to diagnose and identify issues, both hardware and software. It is trusted by many users. Please follow the steps outlined below:

1. Navigate to: https://etrecheck.com and get the free version of EtreCheckPro.
2. Download it. It is a free and trusted app. It is often recommended here on Apple Support Communities. 
3. Open EtreCheck, and before running the report, be sure to check “Allow full Drive Access” at the bottom of the EtreCheckPro window.
4. Run the report, and put it in a post, as seen here: https://discussions.apple.com/docs/DOC-250000211. We will then examine the report for issues in your Mac.

Jack

hi, if it is 8gb or plus then simply refresh the operating system. I also noticed when I upgraded the OS it showed me 1.5 gb less occupied than the previous older one was occupying. and if it is 4gb then use the maximum high sierra OS. it will work absolutely fine.