The folder “com.apple.aned” can’t be opened because you don’t have permission to see its contents.
I have been plaqued by this issue for at least a year now and I found the solution. I first searched the archives and found several users that state to boot to recovery mode and delete the file. This would work if the file was a local file but the problem I had was the Caches folder was in the iCloud .Trashes folder so under recovery mode it is not available.
Instead I was able to open Terminal
Ran sudo su then entered the password
Then CD to the ~Library/Mobile\ Documents/com~apple~CloudDocs/ folder
I found the .Trashes but it would not let it be deleted, so instead I moved/renamed it using the mv command
Then I rebooted and emptied the trash
That fixed it for me!