will adobe illustrator CC 22 and Photoshop CC 19 work with OSX Monterey

Adobe is taking their own sweet time as usual in responding to users needs. Compatibility with Monterey is apparently not a top priority with them.

For that reason, and others, Affinity is my wife's current Adobe replacement. So far it's done everything Adobe did that she needs and their who ecosystem is far more user friendly that Adobe's ever was.

You should be asking on an Adobe forum, not an iMac forum. The users of the Adobe apps that are Monterey users would likely have a better ida.