You can use Disk Utility to create a RAID 0 consisting of all the 2TB drives. Data is striped across the drives for a performance gain.
You can also create a Concatenated JBOD array, which also combines multiple drives, but in a serial manner (e.g. data is written to drive 1 until it's full, then it spills over to drive 2... drive 3, etc.
Neither offers any kind of redundancy - if any single drive in the chain fails you risk losing all your data.
For increased resiliency you can install the drives into a RAID chassis, using something like RAID5 to provide resiliency against drive failure. Once you have this array, it takes care of presenting a single volume to the host system which you can use, letting it take care of spreading data across the drives.