I'm not able to click on some menu options on MacBook Air

Q - " Also, I don't know if this is also related but when I try to click on links in emails, it selects them but an error box pops up to say that it can't be opened. Default browser is Firefox at the moment if that makes a difference. "

A - And yes, make Safari the default Browser

Q - Is this accurate as per user Profile MacBook Air 13″, macOS 12.2

A - Suggest updating to current version 12.4 as this could be related to the other computer issues

A - In good conscience, suggest Make Time Machine Backup   before updating, if not already running Money 12.4

First, there is no reason to ever install or run any 3rd party "cleaning", "optimizing", "speed-up", anti-virus, VPN or security apps on your Mac.  This user tip describes what you need to know and do in order to protect your Mac: Effective defenses against malware and other threats - Apple Community.  

There are no known viruses, i.e. self propagating, for Macs.  There are, however, adware and malware which require the user to install although unwittingly most of the time thru sneaky links, etc.   

Anti Virus developers try to group all types as viruses into their ad campaigns of fear.  They do a poor job of the detecting and isolating the adware and malware.  Since there are no viruses these apps use up a lot of system resources searching for what is non-existent and adversely affect system and app performance.

There is one app, Malwarebytes, which was developed by a long time contributor to these forums and a highly respected member of the computer security community, that is designed solely to seek out adware and known malware and remove it.  The free version is more than adequate for most users.  

That being said uninstall CleanMyMac according to the developer's instructions.

A Fast look and the Etrecheck Report that @ Luis S. suggested.

CleanMyMac X.app

Any Third Party Applications that will interfere with the normal operation of the OS, alter, modify, remove or delete or attempt to do so is an invitation for disaster and comprising the Operating System

Any of the below should be removed as per Developers Instructions 

This will include CleanMyMac and read some of the may posting specific to this Application and the damages it has done and is doing

There has been sufficient advise / suggestions offered, from more than one source, for the User to make an informed and educated choice what the next course of action is required.

The suggestions have been put forth on a volunteer basis, in good faith and in the best interests of the computer.

Try restarting in Safe Mode. Same problem?

If the problem disappears in Safe Mode, there is a software conflict.

Please run Etrecheck and post its full report here. Use the "additional text" button and paste the report into the text box.

+1 on what Old Toad wrote.

You have trusteer and cleanmymac, and this is causing trouble.

Read the text that Old Toad linked to about effective defenses.

Also: you have very old stuff. Do you really use Blackberry? This stuff was built with the 10.7 SDK, so over a decade old... and most likely just a remnant of old days.

Look at all the system extensions - they are mostly very old:

Kernel Extensions:

/Library/Extensions

[Not Loaded] BlackBerryUSBCDCNCM.kext - com.BlackBerry.driver.USBCDCNCM (1.0.14 - SDK 10.7)

[Not Loaded] FTDIKext.kext - com.FTDI.driver.D2XXHelper (1.0 - SDK 10.12)

[Not Loaded] JMicronATA.kext - com.jmicron.JMicronATA (1.1.6)

[Not Loaded] RIMBBUSB.kext - com.rim.driver.BlackBerryUSBDriverInt (2.2.16 - SDK 10.7)

[Not Loaded] BlackBerryVirtualPrivateNetwork.kext - com.rim.driver.BlackBerryVirtualPrivateNetwork (1.0.18 - SDK 10.8)

[Not Loaded] SiLabsUSBDriver64.kext - com.silabs.driver.CP210xVCPDriver64 (3.0.0d1)

[Not Loaded] Wacom Tablet.kext - com.wacom.kext.wacomtablet (Wacom Tablet 6.3.24-1 - SDK 10.12)

[Not Loaded] BJUSBLoad.kext - jp.co.canon.bj.print.BJUSBLoad (10.75.21 - SDK 10.8)

[Not Loaded] CIJUSBLoad.kext - jp.co.canon.ij.print.CIJUSBLoad (16.0.10 - SDK 10.9)

You should consider doing a full backup, then erase and install a clean system, and migrate ONLY the user accounts.

Old cruft that accumulates over the years is bound to fail at some point.

I would not go about erasing the internal drive without a Time Machine backup and a second backup - I also use SuperDuper! to make a full clone.

At this point, and if things are working ok, I would hold off on the reinstall, and take advantage of the time of upgrading to macOS Ventura in the Fall.

You are welcome and thank you too.

Do come back to the Apple Support Communities ( ASC )  in the future, if / or when additional questions may arise