how do I update my Mac Pro OS10.12.6 that was off for years

Depends which OS it qualifies for...

macOS High Sierra - Technical Specifications

General Requirements

• OS X 10.8 or later
• 2GB of memory
• 14.3GB of available storage to perform upgrade*
• Some features require an Apple ID; terms apply.
• Some features require a compatible Internet service provider; fees may apply.

Mac Hardware Requirements

For details about your Mac model, click the Apple icon at the top left of your screen, choose About This Mac. These Mac models are compatible with macOS High Sierra:

• MacBook (Late 2009 or newer)
• MacBook Pro (Mid 2010 or newer)
• MacBook Air (Late 2010 or newer)
• Mac mini (Mid 2010 or newer)
• iMac (Late 2009 or newer)
• Mac Pro (Mid 2010 or newer)
• Don't use FireFox for these links…

macOS High Sierra - Technical Specifications

https://itunes.apple.com/app/macos-high-sierra/id1246284741?mt=1

macOS Mojave 10.14.6 - Technical Specifications

General Requirements

OS X 10.8 or later

2GB of memory

12.5GB of available storage (OS X El Capitan 10.11.5 or later)*

Some features require an Apple ID; terms apply.

Some features require a compatible Internet service provider; fees may apply.

Mac Hardware Requirements

For details about your Mac model, click the Apple icon at the top left of your screen and choose About This Mac. These Mac models are compatible with macOS Mojave:

MacBook (Early 2015 or newer)

MacBook Air (Mid 2012 or newer)

MacBook Pro (Mid 2012 or newer)

Mac mini (Late 2012 or newer)

iMac (Late 2012 or newer)

iMac Pro (2017)

Mac Pro (Late 2013; Mid 2010 and Mid 2012 models with recommended Metal-capable graphics cards)

Don't use FireFox for these links…

https://itunes.apple.com/us/app/macos-mojave/id1398502828?mt=12

MacOS Catalina 10.15.7 - Technical Specifications

General Requirements

OS X 10.9 or later

4GB of memory

12.5GB of available storage (OS X El Capitan 10.11.5 or later)*

Some features require an Apple ID; terms apply.

Some features require a compatible internet service provider; fees may apply.

Mac Hardware Requirements

For details about your Mac model, click the Apple icon at the top left of your screen and choose About This Mac. These Mac models are compatible with macOS Catalina:

MacBook (Early 2015 or newer)

MacBook Air (Mid 2012 or newer)

MacBook Pro (Mid 2012 or newer)

Mac mini (Late 2012 or newer)

iMac (Late 2012 or newer)

iMac Pro (2017)

Mac Pro (Late 2013 or newer)

How to get old versions of macOS - Apple Support

Don't use FireFox for these links…

https://apps.apple.com/gb/app/macos-catalina/id1466841314?ls=1&mt=12

How to upgrade to macOS Catalina – Apple Support

And caution on 10.15 or higher, to see which Apps will no longer work in 10.15 get Go64...

https://www.stclairsoft.com/Go64/

macOS Big Sur - Technical Specifications

General Requirements

OS X 10.9 or later

4GB of memory

35.5GB available storage on macOS Sierra or later*

Some features require an Apple ID; terms apply.

Some features require a compatible internet service provider; fees may apply.

Mac Hardware Requirements

For details about your Mac model, click the Apple icon at the top left of your screen and choose About This Mac. These Mac models are compatible with macOS Big Sur:

MacBook (2015 or later)

MacBook Air (2013 or later)

MacBook Pro (Late 2013 or later)

Mac mini (2014 or later)

iMac (2014 or later)

iMac Pro (2017 or later)

Mac Pro (2013 or later)

Learn about compatibility and how to identify your specific Mac model

Don't use FireFox or WaterFox for this link. it'll mess it up...

https://apps.apple.com/us/app/macos-big-sur/id1526878132?ls=1&mt=12

And caution on 10.15 or higher, to see which Apps will no longer work in 10.15 get Go64...

https://www.stclairsoft.com/Go64/

Monterey…

https://apps.apple.com/us/app/macos-monterey/id1576738294

macOS Monterey on the App Store (apple.com)

https://apps.apple.com/us/app/macos-monterey/id1576738294?mt=12

https://apps.apple.com/us/app/macos-monterey/id1576738294?mt=12

The Age of this computer will Govern what newer version of macOS it will Qualify to install. Use About this Mac from the Apple Icon on Desktop - the required Information will be there.

With the above information in-hand - follow this How to get old versions of macOS and verify what version this computer Qualifies to install.  For Best results use Safari to commence the download as Others may not work.

Safari will open a redirect and open the Apple Store where the download can commence.

Computer Qualify for the Monterey upgrade

macOS Big Sur 11 hardware requirements

macOS Catalina 10.15 hardware requirements

macOS Mojave 10.14 hardware requirements

macOS High Sierra 10.13 hardware requirements

Caution - jumping over all the newer versions and directly to Big Sur  / Monterey on Qualifying computers is Technically possible - there are those who have attempted and were successful. Then there are those who attempted and had less than good results.

If this is a Production or Mission Critical Set-up - a more prudent and measure approach is suggested. 

The above is from observations on the Apple Support Community Forums and IMHO

Tips Big Sir Upgrade Released Nov 2020

Tips Monterey Upgrade  Released Oct 25, 2021

Make Time Machine Backup  is very useful and can be used to Revert to Previous Working macOS

Notation - Mojave is the Last version to support 32 bit applications / extensions and Drivers. Catalina, Big Sur & Monterey supports only 64 bit and there is no workaround.

Suggest using Go64 to find 32 bit application before attempting the upGrade. Some or many of the Application already installed may required update or upGrades to 64 Bit Versions.