What guitar/audio interface?

Hello and welcome to Apple Support Communities, ejbpesca,

If we understand your post correctly, you'd like to know how to tell if a guitar is compatible with GarageBand on your MacBook Air. We’d like to help.

Make sure that your guitar can connect with your MacBook Air using this guide:

Connect an electric guitar to use with GarageBand on Mac - Apple Support

Let us know if that resolves this issue for you.

Thanks for using the Apple Support Communities.

Apogee products are also compatible. I have the One, but it is no longer available.

Thanks for the additional information, ejbpesca. It was helpful.

We took a look at the Focusrite site and located this information: Focusrite product compatibility with macOS 12 “Monterey" on Apple Silicon-based systems - Focusrite Audio Engineering

For more information on their products and use, we recommend contacting Focusrite Support: Submit a request - Focusrite Audio Engineering

All the best.