Installing Monterey

Rebuild the Spotlight index on your Mac

What is “Other” storage on a Mac, and how can I clean it out?

Free up storage space on your Mac

OmniDiskSweeper Safe to use

GrandPerspective 

How to delete Time Machine snapshots on your Mac

See used and available storage space on your Mac

Locate backups of your iPhone, iPad, and iPod touch

Notation - If the user is using a cloning software like Carbon Copy Cloner - suggest tweaking the Safety Net Feature in this software. It may be making addition Snap Shots that are not being Cloned to the Eternal Drive. If this should be the case, these Snap Shot could be using additional space on the drive 

The final word from Apple on Managing the " Other/ System Data “ Category

Other / System Data: Contains files that don’t fall into the categories listed here. This category primarily includes files and data used by the system, such as log files, caches, VM files, and other runtime system resources. Also included are temporary files, fonts, app support files, and plug-ins. You can't manage the contents of this category. The contents are managed by macOS, and the category varies in size depending on the current state of your Mac.

The files that you have control over are located in the Documents, Downloads, Pictures, Music and Movies folders.  You can use either of these two free apps, GrandPerspective  or OmniDiscSweeper, to find the largest files on your drive so you can determine if they can be deleted or moved to an external HD for storage.  

Note: you can empty the Downloads folder after the apps and/or updates that were downloaded have been installed or applied.  Many users have found a couple of Gigabytes of files in their Downloads folder which are no longer needed. 

I'm also guessing Monterey is a rather large operating system.

I think it is only about 4GB larger than the previous.

It needs a lot of empty space to move things around while it does the install. When finished, the OS comes in just under 16GB.

Previous were about 12GB.

RonboyPA wrote:

I can't install Monterey because my disc doesn't have enough space. Any ideas how to address this problem?

Remove your file from the disc until you have enough space.