Apple Mail randomly does a screen refresh.

Hey Esc-in-action,

We'd recommend trying the steps from this article as they can help resolve unexpected issues with apps on your Mac: If an app freezes or quits unexpectedly on Mac

"If an app freezes or quits unexpectedly on Mac

When an app on your Mac stops working, try these suggestions.

1. If an app doesn’t quit as expected, or it’s unresponsive, you can force quit the app (you may lose unsaved changes). Choose Apple menu  > Force Quit, select the app in the dialog that appears, then click Force Quit.
2. If the app quit, reopen it by clicking Reopen in the dialog that appears.
3. Restart your Mac by choosing Apple menu > Restart.
4. Make sure the app is compatible with your version of macOS.
5. Open another file in the app. There may be a problem with the original file.
6. Check for updates to your software.
7. Disconnect any peripheral devices you just connected (for example, a printer). They may not be compatible with your version of macOS.
8. Uninstall any app plug-ins or enhancements from other manufacturers.
9. If you recently updated the app or macOS, a plug-in or enhancement you installed may no longer be compatible.
10. Diagnose problems with your Mac to learn whether hardware you installed, such as additional memory, is incompatible, improperly installed, or defective."

If that doesn't help, you may want to test the issue in safe mode to help narrow that down further. This article explains how: How to use safe mode on your Mac

"How to use safe mode

Determine whether you're using a Mac with Apple silicon, then follow the appropriate steps:

Apple silicon

1. Shut down your Mac.
2. Turn on your Mac and continue to press and hold the power button until you see the startup options window.
3. Select your startup disk, then press and hold the Shift key while clicking “Continue in Safe Mode.”
4. Log in to your Mac. You might be asked to log in again.

Intel processor

1. Turn on or restart your Mac, then immediately press and hold the Shift key as your Mac starts up.
2. Release the key when you see the login window, then log in to your Mac. 
3. You might be asked to log in again. On either the first or second login window, you should see ”Safe Boot” in the upper-right corner of the window."

Thanks!

"R. Philips" - you really are a Troll, aren't you?

Updating the MacBook Pro to v. 12.6.1 (21G217) was of no help in resolving the "Random Screen Refresh" issue. Hopefully others experiencing the issue will respond here or in a related thread, since this is a real issue and deserves legitimate attention.

This Random Refresh is occurring for me in Apple Mail v.16.0 (3696.120.41.1.1)

//dkG

User wrote " MacOS Monterey 12.5.1 "

The current version of Monterey is 12.6.1

It brings several Bug Fixes and also Security Fixes

Outside of the 12.6.1 update is a separate Safari 16.1 update too.

Any of the above maybe directly related to this computer issue

In good conscience - suggest doing  A Time Machine Backup  which is very useful.

OK - I will restate the complaint.

Apple Mail randomly refreshes the screen and resets focus to the message folder from the message.

This behavior has occurred on my MacBook Pro M1 since delivery in June 2022 with stable consumer versions of Mac OS - currently on 12.4 (21F79) and Mail v 16.0 (3696.109.31)

Normally do not reply to a Non Owner of the Original Question which is @ Esc-in-action

The same advise posted in reply the OP would apply to a computer running Monterey 12.4 released May 16, 2022 Monterey macOS 12.4 ( 21F79 )

As the User has pre-determined that running an out dated version of macOS Monterey if ok and that updating to the current version 12.6.1 will not potentially fix this computer issue, it is therefore suggested they seek assistance Directly from Apple via the suppled method below

Get Support Choose a product and we’ll find you the best solution.

Start now and open an Apple Support Ticket as they are Apple Employees to deal will these types of issues .

The user is welcome for the free advise

Have taken enough of the Users' time and wish them good luck with this computer issue

As a test set your "check for mail" interval to a longer setting and see what happens (Turn off check automatically).