Hi Out_fishing,
We'll be glad to help you out with this further. To start, Preview would generally be considered the "native" app for opening PDF files on the Mac. Which specific software are you referring to? There wouldn't be a reason for it to automatically start scrolling. Generally, if it were scrolling with all applications, we might look into some issue causing your Mac to "think" it is being alerted to scroll.
However, if that were the case, you would also likely notice this behavior in Preview as well.
Does this happen with any other file types at all?
From here, boot your Mac into safe mode and see if it happens there. That will cause any 3rd party software you have installed on your Mac not to start up. If one of those programs is causing this, that will let us know.
This shows how to enter safe mode: Start up your Mac in safe mode - Apple Support
Cheers.