iPad Pro 12.9 will not let me swipe up to unlock and does not recognize any screen touch

If your iPad is unresponsive to input, connect your iPad to its Power Adapter and allow the iPad to charge. Then, while still connected to external power, try a forced-restart:

Force restart iPad (models with Face ID or with Touch ID in the top button)

If your iPad doesn’t have the Home button, do the following:

1. Press and quickly release the volume button nearest to the top button.
2. Press and quickly release the volume button farthest from the top button.
3. Press and hold the top button.
4. When the Apple logo appears, release the top button.

Force restart iPad (models with the Home button)

Press and hold the top button and the Home button at the same time. When the Apple logo appears, release both buttons.

If iPad still doesn’t turn on, or if it gets stuck during start up, see the Apple Support article If your iPhone, iPad, or iPod touch won’t turn on or is frozen. Or if your iPad isn’t working correctly after you restart it, see the iPad Support website.

If you continue to experience difficulties, you will need to seek assistance directly from from Apple Support. You can contact the Support Team using the Support link at top-right or bottom-left of this page. Alternatively, you can initiate and manage your support cases using the excellent Apple Support App. If not already installed on your iPad, the App can be downloaded from the App Store:

https://apps.apple.com/gb/app/apple-support/id1130498044

You might also visit the Genius Bar at your local Apple Store or Apple Authorised Service Provider (AASP) - where the technicians will be able to test and assess your iPad:

Genius Bar Reservation and Apple Support Options - Apple

Based on what you've mentioned, it seems like you've already tried the volume button suggestions, but let's try a few more troubleshooting steps to see if we can resolve the issue.

First, let's try a force restart of your iPad. Press and quickly release the volume up button, then press and quickly release the volume down button. Finally, press and hold the power button until the Apple logo appears on the screen. This should force a restart and may help resolve any temporary software glitches causing the touch screen problem.

If the touch screen is still unresponsive after the force restart, it's worth checking if there are any updates available for your iPad's software. Connect your iPad to a Wi-Fi network, go to Settings > General > Software Update, and check if there's an update available. If an update is found, tap "Download and Install" to update your iPad. Sometimes, software updates include bug fixes that can address issues like touch screen responsiveness.

If the issue persists, it's advisable to contact Apple Support directly or visit an Apple Store for further assistance. They have the expertise to diagnose and resolve hardware-related issues effectively. To contact Apple Support directly, simply select the "Support" link on the lower left-hand side of this forum's web page.

Here are a couple of helpful Apple Support articles you can refer to:

1. Force restart iPad

2. Update your iPad

I hope these steps help get your iPad Pro's touch screen back in action! Let me know if you have any further questions or concerns.

If Tesserax’s steps do not work it’s likely the digitizer has gone out which would explain why your touch has stopped working, you’ll want to go to Apple Genius Bar: Genius Bar Reservation and Apple Support Options - Apple

scroll down to hardware help if you need to schedule a Genius Bar appointment.