Hello Green500,
Thank you for your answer. I have removed all but one unsigned apps, storage on my startup disk is fine. Now my machine runs relatively smoothly, although iCloud sync, especially uploading, is still very slow.
I have a system extension that has stuck in after removing the application it belonged to, which míy be the main culprit for my Mac slowing down:
[Running] AdGuard Network Extension - version 2.5.2 (Adguard Software Limited)
Application: /Applications/Adguard.app - version 2.5.2 (Not found!)
Description: AdGuard Network Extension
I tried to uninstall it with systemextensionsctl, following these instructions: https://derflounder.wordpress.com/2020/09/01/uninstalling-macos-system-extensions/. However, it did not work - maybe because it was written in 2020, generations before Sonoma? To uninstall the system extension using systemextensionsctl the first step is to locate the Team and the bundle identifiers for the extension. I followed the instructions for locating the bundle and team identifiers but I stuck here - maybe because the application whose part this extension was had already been removed?
Thanks again.