Computer restarts with panic, busy timeout, IOBlockStorageDriver

I am following multiple lines of thought at the same time.

the first Is that your encryption add-ons could be inserting themselves in the system I/O stream at a point that could be causing delays, and that shows itself as that kernel panic.

the second is that your drive could be defective, thus the suggestions that you need to demonstrate failure(s) without add-ons present. Because getting Apple convinced your drive is defective will be difficult. You should run the diagnostic, but it generally only catches GROSS failures.

NB> I do not recommend you submit your Mac for service COLD. Without the ability to demonstrate the failure on demand, the Genius Bar technicans will run their diagnostics, see no failures, and return your Mac to you, "no failures detected". They are NOT trained to read panic reports.

A better route is to contact Apple support, ask for a Specialist who CAN read your Panic reports, and convince them to DIRECT an Apple service provider to change some stuff, likely the mainboard-with-drive. They can read what is already posted, if you alert them to it, but they do NOT take our word for conclusions. They have their own more rigorous processes.

Official Apple Support



the third is that if your drive DOES need to be changed, your files will NOT be returned to you, so 'having all the backups you want' is what you must have before you submit your Mac for drive replacement.

what I take away from your Etrecheck report is that you are doing a lot of work with gpg encryption, and creating and moving files with that encryption. the tools used are less common.

But what MIGHT be happening is that using some of those tools MIGHT be causing delays in your I/O system reads or writes, producing a kernel panic.

--------

At a minimum, you must be certain you are using the absolute latest versions of all those add-ons, as there have been recent changes to MacOS, some in the File System, that have derailed a LOT of third-party stuff.

to get Apple to provide a replacement drive, you would need to demonstrate a panic or diagnostic failure WITHOUT all your file system oriented add-ons present, such as in Safe Mode, where none are loaded automatically.

¿what is the date of your most recent backup, and by what method?

It really helps if you post the entire Kernel Panic report here using the "Additional Text" icon which looks like a piece of paper on the forum editing toolbar. Post several different Kernel Panic logs so we can see if there is any pattern to them. Kernel Panic logs are located in "/Library/Logs/DiagnosticReports" with file names beginning with "kernel", or ending in ".panic". If there are none in this folder, then check the "Retired" subfolder.

Also, run EtreCheck and post the report here so we can examine it for clues.

That is not definitive, but it does suggest you MAY have drive issues.

Be sure you have a recent trusted backup in a local disk drive. You may need it soon.

the beauty of complete Panic logs is that they offer a VERY detailed look at exactly what happened at one instant in time.

the beauty of Etrecheck diagnostics information list is that it is a DIGEST, that allows for Big Picture look at all problems have occurred recently, and is good for spotting Trends.

One other thing Etrecheck shows immediately is fragments of program that have not been removed properly, under the heading "Clean up". And clean those all up you should, because having PART of a package still installed can cause unsolvable issues.