Smart mailboxes: search multiple keywords and exclude multiple email addresses

I want to setup a smart mailbox that will search for three project keywords (we'll call the words "apple", "orange", and "banana") and also filter out email accounts that send project related emails in large volumes that aren't typically relevant (we'll call these accounts "spam1@spam.com", "spam2@spam.com", "spam3@spam.com").

I'm not sure how to do this with how Smart Mailboxes make you chose "any" or "all" rules to apply. I could do it if it were a mix of both (have a set of rules where any condition could be met, and another set of rules where all conditions must be met). I also can't find a way to include multiple keywords in one rule

e.g. Rule 1 = Entire message contains "apple" or "orange" or "banana", Rule 2 = Sender is not from "spam1@spam.com", "spam2@spam", etc.

As a result, my current mailbox can only search for emails with the keywords but not filter out the spam emails. I have three rules of which any could be met, one to search for each keyword, e.g. Rule 1 = Entire email contains "apple", Rule 2 = Entire email contains "orange", etc. With this "any" constraint in place, I cannot include another rule that would search for emails that do not contain "spam1@spam" else the mailbox would return many emails that aren't actually associated with the project.

Please let me know if there is a workaround for this.

Thanks