Create Smart Mailbox that filters out certain emails while searching for multiple keywords in emails

I want to create a project specific Smart Mailbox that searches for 3 keywords (call them "apple", "orange, and, "banana") in any email while also filtering out a few specific email addresses (call them "spam1@spam", "spam2@spam", and "spam3@spam"). Currently, I can only setup three separate rules to search for "any" of the three keywords, but can't filter out the emails; if I added any of the spam email addresses to an "any" rule-based Smart Mailbox, it would return any email that isn't from that sender but not necessarily related to the project.

Is there a way to have all keywords searched for in one rule and all emails searched for an another? That way, I could use an "all" rule-based mailbox instead. Let me know if this is possible.

Thank you!