If you don't mind watching the beachball spin once in a while you should be OK as long as you spec the MacBook Air with 24GB RAM and a large enough internal SSD. (I'm not saying it will happen ALL the time, but it's likely to happen more than with a MacBook Pro.)
Note that the MacBook Air doesn't have a fan for internal cooling, so you may find the processor gets throttled when its subjected to intense demands for extended periods.
I've never used Blender, so I can't speak to that side of things. Might be best to double check with their support on whether the MacBook Air is up to the task. (I suspect it is, but never hurts to check).