I'm late to party, but allow me to add a couple of thoughts. I agree its probably time for a newer Mac but there may be value in the diagnostic process to avoid similar issues with a newer one, especially if your current issues involve third-party hardware or software.
—You said this started yesterday. Did anything change yesterday? Devices added? Cables changed? SW installs?Etc.
—You have some apps that must "phone hone." Have you tested your internet speed?
—You have Apple's Fusion drive. To me, this data:
Performance:
System Load: 1.45 (1 min ago) 1.11 (5 min ago) 1.30 (15 min ago)
Nominal I/O usage: 0.07 MB/s
File system: 26.57 seconds
Write speed: 591 MB/s
Read speed: 2631 MB/s
does not scream a sick drive. In your iMac model, and based on a lot of Etrecheck drive reports here, expected Fusion performance for a healthy drive is:
- Writes between 600-900MB/sec
- Reads as high as 2000MB/sec.
Your Writes are at the bottom end of the range but close enough to normal. Your Reads are far above expected. A File System score of under about 40 seconds is what one sees for a healthy drive system. Yours did it in 27 seconds.
This is the same EtreCheck data from my 18,3 2017 5K iMac with a 4.2gHz i7 processor and Apple's factory 1TB SSD:
Performance:
System Load: 1.66 (1 min ago) 1.42 (5 min ago) 1.31 (15 min ago)
Nominal I/O speed: 0.23 MB/s
File system: 20.35 seconds
Write speed: 2156 MB/s
Read speed: 2863 MB/s
Pure SSD systems always have faster Writes than Fusion but look how well your Reads compare to a factory SSD.
Is 600MB/sec slow? Well, I have a much earlier Macbook Pro I retrofitted with an old-school SATA 6 SSD. Both its drive scores are just under 500MB/sec and it never feels slow in use.
I can't help but think there is something else contributing to your "slows."
—A very easy test for a possible suspect is to disconnect all USB externals except for your mouse and keyboard, then run a while and see if your Writes score increases. I am seeing issues with older USB devices like USB2 mixed with current devices affecting performance. A USB 3 device connected with a USB 2 cable or hub will run at USB2 speeds.
If performance improves, then reconnect devices one by one to see when speeds drops again.
—Is the Samsung external SSD used as a simple backup disk or something more demanding, like a scratch disk or a boot helper?
—It looks like Cocktail is installed. If so, try disabling it and testing,
—Evict any apps that claim to "clean," etc.
I have no quibble with the others' recommendations but think it would be prudent to know what has slowed this Mac so you can be aware of such issues in the future if it turns out to be a third-party product causing it..