Chrome extension pop-up error message

https://forums.zotero.org/discussion/115141/zotero-connector-conflicts-with-singlefile-extension-in-chromium-based-browsers

https://discussions.apple.com/thread/255978513?answerId=261201811022&sortBy=oldest_first#261201811022

Uninstall Google Chrome for the reason contained in above link

From a similar question where the user floated the idea of this being Malware

Annoying pop-up "There is no application … - Apple Community

If, as you have mentioned you ran Etrecheck

It would normally and possible remove the Malware if there was Malware found

You may consider Posting the Etrecheck Full Report

The more Eyes on this the better - no ?

drsunshine wrote:

It is not Chrome or Zotero. The problem started when I did not have Chrome. Or Google Earth for that matter - which has laos been suggested in other threads. Installing Chrome didn't help either. Double checked and Zotero was only ever installed on my macbook (which has never had the problem). I ran a deep scan using ClamXAV yesterday and it doesnt pick up anything sinister.

Other ideas please!

As the user ( you ) has pre-determined Google Chrome is Not the root cause of this computer issue.

What more can be suggested to persuade you otherwise ?

No doubt, the user is aware that there are no windows like Viruses that effect macOS

The usage of ClamXAV to scan for Viruses just reinforces the possible idea that one is less knowledgeable about how macOS function than they think they are.

Further, should you decide to use and post the Etrecheck Report now or at a later time, we are willing to have a very close look and offer some insights 

Will leave the below ditty for you to think upon.

Windows-like viruses that self-replicate and affect macOS don’t exist because of the underlying UNIX Foundation and permission limitations.

The macOS operating system resides in a sealed and read-only volume that can’t be opened by users or third-party applications.

This antivirus software only protects the developers’ bank accounts and creates problems for users in return.

Mac app security enhancements are sufficient to protect computers from malware.

Adware and malware can affect computers and are often downloaded from “shady” websites or developers who inject them into downloads.

Source: User tip from @Kurt Lang

What is malware? - Apple Community