At work, we have experienced noticeable slowness in a few of our internal websites loading on Safari after upgrading to 18.6.
The same website taking multiple seconds to load on the new version whereas on 18.5 it was just fine.
The issue is experienced by users on an iPad and MacOS.
We have checked the same website on other browsers (Chrome and Firefox to give a few examples), and it's fine on those.
On a further test, a coworker was able to test webkit itself on a linux machine and was able to confirm the slowness for the most recent version of webkit, so it's possible that some of the webkit updates included in Safari 18.6 is the reason for the slowness.