Apple IS admitting that this is a known problem. That's amazing in and of itself. I can't count how many times in the past when there's been a serious problem with some new Apple product (for example, the one where the last two generations of MacBook Air overheats when running video and the processors slow down or lock up) Apple denies or stonewalls.
Our experience indicates that the problem is USB related and affects all 27" displays (at least all 16 we purchased in the US and UK). Sound goes out and the system prefs Sound panel goes nasty-jerky after an indefinite interval. Sleep may or may not be what triggers the issue. We also believe that when the problem manifests it may be overheating the computer. Our observations are with the monitors connected to 27" i7 iMacs. When we noticed that if you continue to run the system after the sound goes out the iMacs sometimes start having a very hard time running video (we first noticed it with Vimeo), the video gets very, very jerky. Very suspicious on an 8 GB 8 core i7 iMacs. We installed iStat Menus 3 which displays output of all the iMac's internal temperature sensors as well as fan speed and processor load. I have no way to establish cause and effect, but some of the temps were a little or a lot higher on iMacs that had a 27" display connected and were actively experiencing the sound failure. Representative Normal/Fail in centigrade with 20º ambient: Board 54/59, CPU 44/52, GPU heatsink 49/62, Primary heatsink 52/62, Secondary heatsink 66/80. Unplug the monitor and restart the computer with the monitor connected but its USB disconnected and you can watch the temps drop. So there seems to be a LOT of heat associated with the problem.
It ***** that these beautiful new 27" monitors have this serious flaw, but at least AppleCare openly admits there is a problem and says Apple engineering is working on it. I'd like to just wait it out, but after getting the shaft on all the MacBook Airs we bought (Apple never fixed the problem so far as we know) I'm returning all the 27" monitors we just bought. We'll replace them when Apple fixes the problem. Sad day... the display is beautiful.