"You can then either manually manage your iPhone on a second computer, or sync different data on different machines (E.g. Music at home, Contacts/Calendar at work)."
http://www.andrewgrant.org/2008/03/30/how-to-sync-an-iphone-with-two-or-more-com puters.html
- On the PC you can find your iTunes folder in your "My Music" (XP) or "Music" (Vista) directory. On the Mac it is in your Music directory.
- For the editing part, I recommend UltraEdit on the PC and a combination of TextExit / HexEdit on the Mac. Any hex editor will do, and you only need to edit files on the second machine.
- After completing these steps you will be able to sync your iPhone with both computers, either by normal syncing or choosing one machine to manually manage your music and videos. Unless you also keep your music libraries in sync, I recommend you do not attempt to normal sync the same types of data on both machines.
On the machine you want to sync with, backup "iTunes Music Library.xml" and "iTunes Music Library" (Tunes Music Library.itl on PC) to a safe location. These are the files you will be modifying.
On the machine your iPhone currently syncs with, open "iTunes Music Library.xml" with a text editor and find the entry between the <string></string> tags, after "Library Persistent ID". In the example below this is 8B6C633F7DACB74B. Copy this entryexactly to a piece of paper, email, temporary file etc. You can then close this file.
iTunes stores your library information in two places. An XML file and a binary file. You now need to change the ID in both so they match your other library.
Make sure iTunes is not running.
On the machine you want to sync with open "iTunes Music Library.xml" in a text editor. Again, find the entry between the <string></string> tags after "Library Persistent ID" and copy this entry exactly. This time you can use the clipboard if you wish.
When you have a copy, replace this entry with the one you copied in part 1. Make sure you do not change anything else, and the length of the entry is 16 characters/digits. Save this file and close it.
In the Hex Editor, open "iTunes Music Library" (Tunes Music Library.itl on PC).
Select "Find and Replace" from the Edit menu. Make sure "Hex" matching is selected (not ASCII). In "Find" enter the ID you took a note of in Part 1. In Replace, enter the ID you copied at the start of Part 2. Choose Replace All, there should be one match.
Save this file and close it.
Start iTunes on the machine you wish to sync with and plug in your iPhone. When you select "Manually manage music and videos" you will no longer be prompted to erase your data, nor will the files on your iPhone be grayed out.
Previously I’ve found that intentionally corrupting the binary "iTunes Library" file (e.g. replacing it with a text file) would cause iTunes to regenerate it using the XML data. This no longer appears to work for me in iTunes 7.6.1 and the "repaired" file only contains a few songs. This may be because I keep my music on an external drive but I cannot say for sure. Either way, patching the binary file does not take long and removes any chance of later problems.