Here is my solution to this issue. Granted this is not the best solution, but a stop gap until Apple Corrects this in a future update.
Go to System Prefrences and select Energy Saver. Set your computer to slepp to Never. After two days of working with this issue with an AppleCare specialist, this is the solution. I believe that something is getting mucked up after the computer wakes from sleep mode and causing the freeze or lock up. These are the steps I have taken thus far.
- Reinstalled Lion
- Emptied my Library, User Library, & System Cache
- Reset the PRAM
- Run in Safe Mode
- Repaired Permmisions
- Repared the Disk
- Switched iTunes to 32-Bit Mode
The other alternative is to downgrade back to Snow Leopard or install Windows 7 on a Boot Camp partition (JK).
This is a certain show stopper for Lion.